Complement-Fixation Test with Witebsky, Klingenstein, Kuhn (WKK) or Similar Antigens: A Modified Technique

The Value of the Complement-Fixation Test in the Diagnosis of Kala-Azar

In a previous publication (Sen Gupta, 1943), the results of the complement-fixation test using the original Witebsky, Klingenstein, Kuhn (WKK) antigen were reported. Reference was also made about the preparation of the antigen according to the WKK method. It was shown that a complement-fixation test of marked degree of ' specificity' for kala-azar had been evolved. In order to investigate furth...

Complement Fixation in Kala-Azar with the WKK Antigen

In our present issue we publish two articles in which the value of a complement-fixation test in early diagnosis of kala-azar is stressed. The antigen used is that of Witebsky, Klingenstein and Kuhn prepared from the tubercle bacillus, and originally intended for complement-fixation tests in tuberculosis. In tuberculosis, however, the results are very poor. Work in South America, however, revea...

A Note on Complement-Fixation Test in Leprosy and Kala-Azar with Witebsky, Klingenstein and Kuhn (W.K.K.) Antigen

A Note on Complement-Fixation Test in Leprosy and Kala-Azar with Witebsky, Klingenstein and Kuhn (W. K. K.) Antigen

Studies on Influenza Virus

Influenza complement fixation tests designed for use with ferret serum are described. Complement-fixing antigens derived from influenza ferret lungs were unsatisfactory due to their low content of soluble antigen; those prepared from mouse lungs or developing chick embryo membranes proved to be better antigenically and were reliable when the various reagents in the test were properly adjusted t...